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Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

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WAKE-UP Time for Thrombolysis in Acute Stroke?

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By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

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Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”


By Olivier Lucar
October 16, 2018

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By Connor Emdin
September 26, 2018

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Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

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Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.SWEATSHIRT PYREX MEN PY33302 blueE-S Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?

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By Martina McGrath, MD
July 18, 2018

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Gelert Heren BE 127246 polyester mouw Lange Zwart jasje 9cfefsela86690-Coats & Jackets

Item specifics

New with tags: A brand-new, unused, unworn and undamaged item in the original packaging (such as the original box ... Read moreabout the condition
Geslacht: Man
Type maat: Regolare Merk: Gelert
Materiaal: 100% polyester Model: GELERT GIACCA UOMO BLK/GELERT BLUE
Seizoen: Zie de beschrijving MPN: 127246
Afmetingen: Zie de beschrijving Overheersende kleur: Zwart
Halslijn: Zie de beschrijving Type: Jasje
Sluiting: Zie de beschrijving Stijl: Zie de beschrijving
Thema: Zie de beschrijving Mouwlengte: Lange mouw
Gelert Heren jasje Zwart Lange mouw polyester   127246 BE

Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

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By Connor Emdin
June 27, 2018

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Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

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By Martina McGrath, MD
June 5, 2018

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By Lea Borgi, MD
May 16, 2018

Men's 44R Sanyo Trench Coat Sahara Removable Wool Lining 4-Season MINT VESTE HOMME OBEY ANYWAY 126251638 126251638 ANORAK TRIBES greenKorea Mens Leather lamb wool fur lining Lapel Collar Motorcycle Short new Coat Continue reading “Does Menu Labeling Lead to Healthier Food Choices?”